Divigel

Contains the active ingredient:Micronized 17-N2-Estradiol(natural) , which is a naturally occuring form of the main female sex-hormone,oestrogen.

Womens' ovaries-gradually produce less and less-oestrogen in the period up to the-menopause, and oestrogen-blood levels decline as a result. The declining levels of-oestrogen can cause distressing-symptoms, such as irregular periods, hot-flushes, night sweats, mood swings and vaginal-dryness or itching.

Oestrogen(in this case in the form of-estradiol) can be given as a supplement to replace the falling levels in the body and help reduce these distressing-symptoms of the-menopause. This is known as hormone-replacement therapy (HRT). HRT-is usually only required for short-term relief from menopausal-symptoms and its use should be reviewed at least once a year with your doctor.

HRT-is also sometimes used to prevent-osteoporosis in postmenopausal-women. The declining level of oestrogen-at-menopause can affect the bones, causing them to become thinner and more prone to breaking. Oestrogen-supplements help prevent bone loss and fractures that may occur in women in the years after-menopause.

It is an-oestrogen-only form of-HRT. The gel is applied to the skin and the-estradiol is absorbed through the skin into the-bloodstream.

What is it used for?

Hormone-replacement therapy to relieve symptoms-of the-menopause.

As it only contains-oestrogen, It can be used on its own by women who have had a-hysterectomy. Women who have not had a-hysterectomy should also be prescribed-a-progestogen medicine-to take with this medicine, for the last 12 to 14 days of each month. This is because oestrogen-stimulates the growth of the womb-lining (endometrium), which can lead to endometrial-cancer if the growth is unopposed. A progestogen-is given to oppose oestrogen's effect on the womb lining and reduce the risk of cancer, though it does not eliminate this risk entirely. This is known as combined-HRT. If a woman has had her womb surgically removed (a hysterectomy), endometrial-cancer is not a risk, and a-progestogen is not necessary as part of-HRT (unless the woman has a history of-endometriosis).

Direction:

Divigel-can be used for continuous,cyclical, sequential-treatment.

The usual starting dose is estradiol-1 mg (1 g gel) daily but the selection of the initial dose can be based on the severity of the patients'symptoms. 

Administration: Divigel-is a gel for transdermal-use.

Apply on dry and clean skin.

The Divigel-dose is applied once daily, on the skin of the lower trunk or the right or left thigh, on alternate days. The application surface should be 1-2 times the size of a hand. Divigel-should not be applied on the breasts, on the face or irritated skin. After application, the gel should be allowed to dry for a few minutes and the application site should not be washed within 1 hr. Contact of the gel with the eyes should be avoided. Hands should be washed after application.

Manufactured by-Orion,Thailand

Size : 28 sachets /box